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Unique to CLAMS is its ability to accurately account for food spillage. While important, some tests require a more traditional animal setting which allows for bedding and the delivery of food that more closely matches a home cage environment. CLAMS-HC is a home cage implementation of CLAMS that maintains the features found in our premiere product. CLAMS-HC is designed to be affixed to any standard animal cage and provides an adaptable test environment with snap-in modules to support a broad array of physiological and behavioral monitoring capabilities.

Animal Activity Feeding and Drinking Monitor Automated Food and Water Access Core Body Temperature and Heart Rate by Telemetry Body Mass Monitor Wheel Running Environmental Enclosure Sleep Analysis Statistical Software CLAX Columbus Instruments Oxymax system is the leading open circuit indirect calorimeter for lab animal research. The measurement of oxygen may be performed by these technologies supported by Oxymax: Paramagnetic O Sensor - [high speed] Provides full 0-100% range and high speed response Carbon Dioxide - is sensed by single beam non-dispersive IR (NDIR). 9 4216-4226 Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo Yue Wu, Ping Song, Wencheng Zhang, Junhui Liu, Xiaoyan Dai, Zhaoyu Liu, Qiulun Lu, Changhan Ouyang, Zhonglin Xie, Zhengxing Zhao, Xiaozhen Zhuo, Benoit Viollet, Marc Foretz, Jiliang Wu, Zuyi Yuan & Ming-Hui Zou Nature Medicine (2015), doi:10.1038/nm.3826 Uncoupling Protein 1 and Sarcolipin Are Required to Maintain Optimal Thermogenesis and Loss of Both Systems Compromises Survival of Mice Under Cold Stress Leslie A. M115.637603 Coordination of the transcriptome and metabolome by the circadian clock Kristin L. The combination of the Zirconia Oxide based oxygen sensor and high speed single beam NDIR carbon dioxide sensing provides a chamber measurement in 20 seconds. 11 2516-2524 Superimposition of Postnatal Calorie Restriction Protects the Aging Male Intrauterine Growth- Restricted Offspring from Metabolic Maladaptations Yun Dai, Shanthie Thamotharan, Meena Garg, Bo-Chul Shin and Sherin U. CLAMS-HC provides an alternate housing solution that makes use of standard animal cages that support bedding and maintains the use of established standard animal cage cleaning protocols. CLAMS-HC does not require any modification to your standard animal cage.

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  1. For the communication of components in our engine we used messages, events or let them directly search for components implementing a specified interface, which is illustrated in the following diagram: In component-based architecture we were mostly concerned about the component intercommunication, like the player movement for example: Should the Mover-component manipulate the position directly or send movement-messages?